WebSep 2, 2007 · HYPERTENSIVE Cyp4a10 (-/-) MICE SHOW INCREASES IN THE GATING ACTIVITY OF THE RENAL EPITHELIAL SODIUM CHANNEL The decreased levels of urinary epoxygenase metabolites and the salt-sensitive nature of the animal's blood pressure, suggested a potential role for the EETs in Cyp4a10(-/-) hypertension. WebAug 23, 2024 · ChIP quantitative PCR and promoter assay revealed that REV-ERBα is the transcriptional repressor of Cyp4a10 and Cyp4a14. Rev-Erbα-/- hepatocytes had a marked induction of both Cyp4a genes and lipid accumulation. REV-ERBα agonist SR9009 or CYP4A antagonist HET0016 attenuated Cyp4a induction by ethanol and prevented …
CYP4A in tumor-associated macrophages promotes pre …
WebPrimePCR™ Template for SYBR® Green Assay: Cyp4a10, Mouse Reaction: 200 x 20 µl reactions desalted Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay. Retinol metabolism HETE and HPETE biosynthesis and metabolism WebNov 2, 2016 · CYP4A10 and CYP4A14 are two key enzymes for ω-oxidation of hepatic fatty acids. The effects of rifampicin on the expression of hepatic Cyp4a10 and Cyp4a14 were … image towing
Cyp4a10 Polyclonal Antibody (PA3-033) - thermofisher.com
WebOct 11, 2014 · CYP4A10/11/14/12A/22 Antibodies. Antibodies that detect CYP4A10/11/14/12A/22 can be used in several scientific applications, including Immunohistochemistry, ELISA, Immunocytochemistry and Western Blot. This Rabbit polyclonal antibody targets CYP4A10/11/14/12A/22 in Rat, Mouse and Human samples, … WebApr 15, 2000 · In Cyp2e1 –/– mice with NASH (but not in wild-type mice), CYP4A10 and CYP4A14 were upregulated. Furthermore, hepatic microsomal lipid peroxidation was … WebDec 1, 2011 · 5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR), a prodrug activator of AMP-activated protein kinase (AMPK), increased hepatic expression of cytochrome P450 4a10, 4a14, and 4a31 mRNAs 2-, 3-, and 4-fold, respectively, and liver microsomal lauric acid ω-hydroxylation increased 2.8-fold. Likewise, mRNA levels of the … list of different gender types